BDBM394123 US9975861, 3::US9975861, 4::US9975861, 5

SMILES CCNC1=NC(NC(=O)N1)c1ccc(F)cc1

InChI Key InChIKey=XWRLROSVVBGPPA-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 394123   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Fondazione Istituto Itaiano Di Tecnologia

US Patent
LigandPNGBDBM394123(US9975861, 3 | US9975861, 4 | US9975861, 5)
Affinity DataIC50:  7.11E+3nMAssay Description:Human recombinant GSK-3β was purchased from Millipore (Millipore Iberica S.A.U.) The prephosphorylated polypeptide substrate was purchased from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Fondazione Istituto Itaiano Di Tecnologia

US Patent
LigandPNGBDBM394123(US9975861, 3 | US9975861, 4 | US9975861, 5)
Affinity DataIC50:  1.26E+4nMAssay Description:Human recombinant GSK-3β was purchased from Millipore (Millipore Iberica S.A.U.) The prephosphorylated polypeptide substrate was purchased from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Fondazione Istituto Itaiano Di Tecnologia

US Patent
LigandPNGBDBM394123(US9975861, 3 | US9975861, 4 | US9975861, 5)
Affinity DataIC50:  7.11E+3nMAssay Description:Inhibition of human acrosin and control activity being 11.3 umol/min/mgMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Fondazione Istituto Itaiano Di Tecnologia

US Patent
LigandPNGBDBM394123(US9975861, 3 | US9975861, 4 | US9975861, 5)
Affinity DataIC50:  1.57E+4nMAssay Description:Human recombinant GSK-3β was purchased from Millipore (Millipore Iberica S.A.U.) The prephosphorylated polypeptide substrate was purchased from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Fondazione Istituto Itaiano Di Tecnologia

US Patent
LigandPNGBDBM394123(US9975861, 3 | US9975861, 4 | US9975861, 5)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human recombinant GSK3beta using prephosphorylated polypeptide GSM as substrate incubated for 30 mins in presence of ATP by Kinase-Glo ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed